We have just published a paper in Nature Communications, MINFLUX microscopy resolves subunits of the cardiac ryanodine receptor and its 3D orientation in cells.
We present purely optical data of RyR2 distribution with sub-molecular resolution by applying 3D MINFLUX microscopy. Using …
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We have just published a paper in ASC Photonics, Optimizing Effective Labeling Efficiency in MINFLUX 3D DNA-PAINT Microscopy by Maximizing Marker Detection Probability.
The gist is that we noticed needing considerable imaging time to exhaustively image the markers in densely labeled samples …
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For users mainly interested in the stable releases of python-microscopy and PYME-extra for usage as is we now recommend a pip based install.
We highly recommend installing into a fresh virtual environment as can be generated with conda and related tools:
if you …
The brand new Abberior Super-resolution microscope is now installed in the Department of Physiology, Uni Bern.
Everything arrived in 3 massive crates and after a little bit of sweating we got the breadboard with all optics assembled already on it into the …
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The top image shows the Abberior Super-resolution microscope that enables fluorescence imaging with truly molcular resolution. The panel below shows proteins that are part of the nuclear pore complex (NPC) and exhibits the very high 3D resolution of the MINFLUX …
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Phd student Carl Harrison has written a very nice perspective for the spring edition of Physiology News.
Carl gives an overview of our work on super-resolution imaging of clusters of RyR2 and why physiologists, mathematical modelers, biologists at large and everybody else should care about it.
For info, the sleeping …
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Our paper on using quenchers to simplify multiplexed super-resolution has just appeared online in Nano Research. The investigation was lead by Tobias Lutz.
It is the result of a collaboration with the Pagliara group at the LSI and Lorenzo Di Michele at the Cavendish.
The method we present in the …
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We have just published our paper on fully quantitative imaging of ryanodine receptors in Cell Reports. A good start to 2018! Using DNA based labeling we were able to push the optical resolution to new limits.
Here are our highlights:
On Nov 28 we have published a a paper on human neuromuscular junctions in the journal Cell Reports. This study was led by our colleague Tom Gillingwater. We contributed the super-resolution data and assisted with the quantitative evaluation of the imaging data.
And we got the cover! The picture above …
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We have just published a neat little paper in ASC Nano, a journal that should be well known to all nano aficionados.
This is a study we performed in collaboration with our colleague Charlie Jeynes from the Centre for Biomedical Modelling and Analysis. Charlie has written a neat summary for …
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